Omaha Police responded to a call at 21st and Burt Street just after 3 o'clock Friday afternoon.
Police say Aquilee Muse was walking with several other teenagers when they were confronted by two other teens. Muse was involved in a physical altercation with them and suffered a head injury.
He was transported to a hospital in critical condition and he was pronounced brain dead on Tuesday morning. His family was preparing to take him off the ventilator Tuesday afternoon.
Muse's family released a statement through the hospital on Tuesday: "Keke was a wonderful, loving and funny kid. He could put a smile on anyone's face. We always said that he should have his own comedy show. He loved to eat cereal, but more importantly, he loved his family and friends. He was deeply involved with church, and carried his Bible in his backpack. We love him, and will miss his big, bright smile every day. During this difficult time, we ask you to please respect our family's privacy as we continue to grieve."
Two juvenile suspects have been taken into custody, but police haven't released their names yet